Publications in 2017

Publications in 2017

Pentraxins in the activation and regulation of innate immunity.
Daigo K, Inforzato A, Barajon I, Garlanda C, Bottazzi B, Meri S, Mantovani A. . Immunol Rev. (2016) Nov DOI: 10.1111/imr.12476.

Poly(Lactic Acid) Nanoparticles Targeting α5β1 Integrin as Vaccine Delivery Vehicle, a Prospective Study.
Dalzon B, Lebas C, Jimenez G, Gutjahr A, Terrat C, Exposito JY, Verrier B, Lethias C. PLoS One. (2016) Dec DOI: 10.1371/journal.pone.0167663

BCG – old workhorse, new skills.
Gengenbacher M, Nieuwenhuizen NE, Kaufmann S. Curr Opin Immunol. (2017) Jul doi: 10.1016/j.coi.2017.06.007.

Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children
Gjøen JE, Jenum S, Sivakumaran D, Mukherjee A, Macaden R, Kabra SK, Lodha R,Ottenhoff THM, Haks MC, Doherty TM, Ritz C, Grewal HMS. Sci Rep. (2017) Jul DOI: 10.1038/s41598-017-05057-x.

Nasal IgA Provides Protection against Human Influenza Challenge in Volunteers with Low Serum Influenza Antibody Titre.
Gould VMW, Francis JN, Anderson KJ, Georges B, Cope AV, Tregoning JS. Front Microbiol. (2017) May DOI: 10.3389/fmicb.2017.00900.

Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses.
Gutjahr A, Papagno L, Nicoli F, Lamoureux A, Vernejoul F, Lioux T, Gostick E, Price DA, Tiraby G, Perouzel E, Appay V, Verrier B, Paul S. J Immunol. (2017) Jun DOI: 10.4049/jimmunol.1602131.

Accelerating tuberculosis vaccine trials with diagnostic and prognostic biomarkers
Kaufmann S,Weiner J,Maertzdorf J. Expert Rev Vaccines. (2017) DOI: 10.1080/14760584.2017.1341316

Safety Profile and Immunologic Responses of a Novel Vaccine Against Shigella sonnei Administered Intramuscularly, Intradermally and Intranasally: Results From Two Parallel Randomized Phase 1 Clinical Studies in Healthy Adult Volunteers in Europe.
Launay O, Lewis DJM, Anemona A, Loulergue P, Leahy J, Sciré AS, Maugard A, Marchetti E, Zancan S, Huo Z, Rondini S, Marhaba R, Finco O, Martin LB, Auerbach J, Cohen D, Saul A, Gerke C, Podda A. EBioMedicine. (2017) DOI: 10.1016/j.ebiom.2017.07.013.

Safety and Immunogenicity of the Recombinant Mycobacterium bovis BCG Vaccine VPM1002 in HIV-Unexposed Newborn Infants in South Africa.
Loxton AG, Knaul JK, Grode L, Gutschmidt A, Meller C, Eisele B, Johnstone H, van der Spuy G, Maertzdorf J, Kaufmann SH, Hesseling AC, Walzl G, Cotton MF, VPM Study Group. Clin Vaccine Immunol. (2017) Feb DOI: 10.1128/CVI.00439-16.

Severity of Mycobacterium tuberculosis-caused pathogenesis as a function of co-infection and environmental parameters.
Majlessi L. Mucosal Immunology. (2017) DOI: 10.1038/mi.2016.40

Colonization with Helicobacter is comcomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis.
Majlessi L, Sayes F, Bureau JF, Pawlik A, Michel V, Jouvion V, Huerre M, Severgnini M, Consolandi C, Peano C, Brosch R, Touati E, Leclerc C. Mucosal Immunology. (2017); doi: 10.1038/mi.2016.14

Interactions between Type 1 Interferons and the Th17 Response in Tuberculosis: Lessons Learned from Autoimmune Diseases.
Mourik BC, Lubberts E, de Steenwinkel JEM, Ottenhoff THM, Leenen PJM. Front Immunol. (2017) Apr DOI: 10.3389/fimmu.2017.00294.

“Inflamm-aging” influences immune cell survival factors in human bone marrow.
Pangrazzi L, Meryk A, Naismith E, Koziel R, Lair J, Krismer M, Trieb K, Grubeck-Loebenstien B. European Journal of Immunology. (2017) doi: 10.1002/eji.201646570

Increased IL-15 Production and Accumulation of Highly Differentiated CD8+ Effector/Memory T Cells in the Bone Marrow of Persons with Cytomegalovirus.
Pangrazzi L, Naismith E, Meryk A, Keller M, Jenewein B, Trieb K, Grubeck-Loebenstein B. Front Immunol. (2017) Jun DOI: 10.3389/fimmu.2017.00715

Multi-level Strategy for Identifying Proteasome-Catalyzed Spliced Epitopes Targeted by CD8+ T Cells during Bacterial Infection.
Platteel ACM, Liepe J, Textoris-Taube K, Keller C, Henklein P, Schalkwijk HH, Cardoso R, Kloetzel PM, Mishto M, Sijts AJAM. Cell Rep. (2017) Aug DOI: 10.1016/j.celrep.2017.07.026.

Specific and Efficient Uptake of Surfactant Free Poly (Lactic Acid) Nanovaccine Vehicles by Mucosal Dendritic Cells in Adult Zebrafish after Bath Immersion.
Rességuier J, Delaune E, Coolen AL, Levraud JP, Boudinot P, Le Guellec D, Verrier B. Front Immunol. (2017) Feb DOI: 10.3389/fimmu.2017.00190.

Epigenetic regulation of the extrinsic oncosuppressor PTX3 gene in inflammation and cancer.
Rubino M, Kunderfranco P, Basso G, Greco CM, Pasqualini F, Serio S, Roncalli M, Laghi L, Mantovani A, Papait R, Garlanda C. Oncoimmunology. (2017) May DOI: 10.1080/2162402X.2017.1333215.

Systematic Investigation of the Role of Surfactant Composition and Choice of oil: Design of a Nanoemulsion-Based Adjuvant Inducing Concomitant Humoral and CD4+ T-Cell Responses. 
Schmidt ST, Neustrup MA, Harloff-Helleberg S, Korsholm KS, Rades T, Andersen P, Christensen D, Foged C. Pharm Res. (2017). doi: 10.1007/s11095-017-2180-9

Human and Mouse Hematopoietic Stem Cells Are a Depot for Dormant Mycobacterium tuberculosis
Tornack J, Reece S, Bauer W, Vogelzang A, Bandermann S, Zedler U, Sting G, Kaufmann S, Melchers F. Plos One (2017) doi: 10.1371/journal.pone.0169119

Long-term maintenance of diphtheria-specific antibodies after booster vaccination is hamperedby latent infection with Cytomegalovirus.
Weinberger B,Keller M,Grubeck-Loebenstein B. Immun Ageing.(2017) Jun DOI: 10.1186/s12979-017-0099-y

Weinberger B, Bueno V, Lord J, Jackson T. Effects of ageing on the vaccination response. The Ageing Immune System and Health. (2017) ISBN 978-3-319-43365-3.

Weinberger B. Vaccines for the elderly: Current use and future challenges. Submitted

Simultaneous Subcutaneous and Intranasal Administration of a CAF01-Adjuvanted Chlamydia Vaccine Elicits Elevated IgA and Protective Th1/Th17 Responses in the Genital Tract.
Wern JE, Sorensen MR, Olsen AW, Andersen P, Follmann F. Front Immunol. (2017) doi: 10.3389/fimmu.2017.00569.

Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity. Immunity.
Zhivaki D, Lemoine S, Lim A, Morva A, Vidalain PO, Schandene L, Casartelli N, Rameix-Welti MA, Hervé PL, Dériaud E, Beitz B, Ripaux-Lefevre M, Miatello J, Lemercier B, Lorin V, Descamps D, Fix J, Eléouët JF, Riffault S, Schwartz O, Porcheray F, Mascart F, Mouquet H, Zhang X, Tissières P, Lo-Man R. (2017) Feb DOI: 10.1016/j.immuni.2017.01.010.